Stem Cell News

The healing potential of stem cells

 
Stem Cell Advantages


What is a Stem Cell Therapy?
 
A stem cell therapy is a treatment that uses stem cells, or cells that come from stem cells, to replace or to repair a patient’s cells or tissues that are damaged. The stem cells might be put into the blood, or transplanted into the damaged tissue directly, or even recruited from the patient’s own tissues for self-repair. Stem cells offer the opportunity of transplanting a live source for self-regeneration. In tx-bridge, we choose adult stem cells for clinical use.

No matter how big a human becomes, it all began with an ovum and a sperm cell. This means that cells exist which have the potential to form a complete human. The first cells to arise from a fertilized ovum are described as totipotent ("potent for everything"). After a few days in the womb, the blastocyst forms. The cells contained in it are called embryonic stem cells. They are still very unspecialized and have the ability to divide endlessly and to develop into all of the 220 human cell types. However, a whole human cannot arise from these few cells. They have lost their toti-virility and are described as pluripotent ("potent for a lot"). As soon as the human's development is completed, these former all-arounders will have changed into mature, differentiated cells taking over a specific function in our body, for example neurocytes which conduct electric impulses, muscle cells which contract and the ß-cells of the pancreas which produce insulin.

However, skin renews itself throughout adulthood, injuries heal and hair grows. Right to the end of our lives, we have cells which are very unspecialized, can divide often and help the organism to regenerate and repair itself. These cells are called adult stem cells. To date, adult stem cells have been found in nearly every body tissue, for example in the skin, the brain, the blood, the liver and the bone marrow.

Biological function of adult stem cells

If body tissue is damaged, stem cells head for the damaged area and advance the process of healing. However, day-to-day processes in the human body also rely on stem cells: our erythrocytes only live for about 120 to 130 days, by which time they have become too old, cannot transport enough oxygen and have to be replaced. This task is taken over by the hematopoietic stem cells that can be found in the bone marrow. According to theoretical calculations, about 350 million new erythrocytes are formed every minute. Most of the other somatic cells are also replaced regularly: liver cells after 10 to 15 days, white blood cells after 1 to 3 days.

In theory, the body has its own repair system. So why do people still become terminally ill? And why does the organism age if it has the ability to regenerate itself?

Stem cell differentiation schema

Limits of regeneration

One established theory is that special messengers lure adult stem cells to the damaged area; However, they often do not arrive in sufficient numbers, or may even fail to arrive at all because the artery is blocked. The damaged area then only heals very slowly, or may not heal at all if the cause of the disease is not eradicated. It might also be possible that some diseases develop covertly and are not recognized as being in need of repair. Another problem: adult stem cells also age. They have much higher regeneration potential than differentiated somatic cells, but it seems that this potential is exhausted after 130 years at the latest. Up to now, the oldest woman in the world lived in France and reached 122 years of age. The process of aging cannot be stopped. However, with the help of modern medicine, it is possible to abstract stem cells from the body, to clean them, concentrate them and then apply them to the diseased area. In many cases, the physiological healing process can be enhanced.

Cell Medicine arranges celluar therapy for patients with the following conditions:
 
  • Peripheral vascular disease  
  • liver disease
  • Nephropathia
  • Diabetes
  • Diabetic complications
  • SLE
  • Autoimmune disease